What Is Astaxanthin?
Derived from Hawaiian Haematococcus pluvialismicroalgae
cultivated under pristine conditions, esterfied
astaxanthin is a stable, powerful, fat-soluble antioxidant
from the carotenoid family. Haematococcus algae
produces astaxanthin to protect itself against ultraviolet
induced free radical damage.*
Features of Astaxanthin Include:
Enhanced Antioxidant Capacity:
Astaxanthin is different
from beta-carotene in that it has two additional oxygenated
groups on each of its ring structures, enhancing its ability
to scavenge free radicals. It is believed to be several
hundred times more effective than vitamin E in neutralizing
singlet oxygen molecules and has been shown to
exert greater antioxidant activity than both zeaxanthin
Bioavailability And Stability:
BioAstin® astaxanthin is
formulated in a base of safflower oil to enhance
bioavailability. Vitamin E and rosemary are added to
Astaxanthin has been and will continue
to be clinically studied.
The producers of BioAstin® hold three patents for
use as a human nutraceutical. US Patents 6,258,855,
6,344,210 and 6,433,025. BioAstin® is a registered
trademark of Cyanotech Corporation.
Uses For Astaxanthin
Astaxanthin protects the phospholipid
membranes of cells from oxidative damage. In a
recent U.S. study, it demonstrated the ability to cross the
blood brain barrier and protect the retina in animals,
suggesting its potential for supporting the brain and
nervous system from free radical damage. In one animal
study, astaxanthin helped to maintain a healthy bacterial
environment in the stomach. *
Initial trials with astaxanthin suggest that it
may boost the skin’s natural antioxidant defenses against
ultraviolet induced free radicals. In a human clinical
evaluation, supplementation with BioAstin® astaxanthin
for two weeks provided significant antioxidant protection
for the skin. In cell cultures, astaxanthin provided greater
protection than both beta-carotene and lutein, in part by
supporting catalase and superoxide dismutase activity.
Astaxanthin may also moderate the activity of polyamines
generated by exposure to sunlight.*
In one double-blind placebo controlled
trial, BioAstin® astaxanthin significantly supported joint
comfort in human volunteers. The results of another
human clinical trial suggest that BioAstin® supported knee
comfort and joint function after strenuous leg exercises.
Subjects in a third study using BioAstin® reported
enhanced wrist nerve comfort.*
Enhanced dietary concentrations of
astaxanthin have demonstrated the ability to support
healthy immunoglobulin activity and immune function.
Additional studies suggest astaxanthin's immune and
cellular support potential.*
Lipid And Cardiovascular Support:
In another animal
study, astaxanthin supported healthy lipid metabolism.
Other studies are in progress to evaluate further its
cardiovascular support properties. *
Source for Astaxanthin
Haematococcus pluvialis microalgae cultivated under
highly controlled conditions; vitamin E (d-alpha
Potential Side Effects Or Precautions - Astaxanthin
At this time, there are no known side effects or precautions.
If pregnant or lactating, consult your physician before taking
Potential Drug Interactions - Astaxanthin
At this time, there are no known adverse reactions when
taken in conjunction with medications.
Ingredients and Dosage
each softgel capsule contains
astaxanthin -4 mg.
(naturally derived from Haematococcus pluvialis microalgae)
lutein (naturally occurring) - 40 mcg.
vitamin A (as beta carotene) (naturally occurring) - 65 i.u.
vitamin E (d-alpha tocopherol) - 50 i.u.
rosemary liquid extract,
high oleic safflower oil,
1–3 capsules per day, with meals.
1. Nir Y, et al. Effect of an astaxanthin containing product on rheumatoid
arthritis. Journal of the American College of Nutrition 2002
2. Jyonouchi H, Sun S, Gross M. Effect of carotenoids on in vitro
immunoglobulin production by human peripheral blood mononuclear cells:
astaxanthin, a carotenoid without vitamin A activity, enhances in vitro
immunoglobulin production in response to a T-dependent stimulant and antigen.
Nutr Cancer 1995;23(2):171-83.
3. Tanaka T, Kawamori T, Ohnishi M, Makita H, Mori H, Satoh K, Hara A.
Suppression of azoxymethane-induced rat colon carcinogenesis by dietary
administration of naturally occurring xanthophylls astaxanthin and canthaxanthin
during the postinitiation phase. Carcinogenesis1995 Dec;16(12):2957-63.
4. Lim BP, Nagao A, Terao J, Tanaka K, Suzuki T, Takama K. Antioxidant
activity of xanthophylls on peroxyl radical-mediated phospholipid peroxidation.
Biochim Biophys Acta. 1992 Jun 22;1126(2):178-84.
5. Jyonouchi H, Sun S, Iijima K, Gross MD. Antitumor activity of astaxanthin
and its mode of action. Nutr Cancer. 2000;36(1):59-65.
6. Jyonouchi H, Zhang L, Gross M, Tomita Y. Immunomodulating actions of
carotenoids: enhancement of in vivo and in vitro antibody production to
antigens. Nutr Cancer. 1994;21(1):47-58.
7. Healthnotes Clinical Essentials. Copyright 2004. Healthnotes, Inc.
*This is a statement of nutritional support. This statement has not been
evaluated by the Food & Drug Administration. This product is not intended to
diagnose, treat, cure or prevent any disease.
This information is for educational purposes only. Consult your physician for
any health problems.
Source: Product Information Sheet from Pure Encapsulations
Manufacturers continually change product
specifications. While we try our best to keep product descriptions up to date,
they do not necessarily reflect the latest information available from the
manufacturer. We are not responsible for incorrect or outdated product
descriptions and/or images.
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