Alpha Lipoic Acid

What Is Alpha Lipoic Acid?

Alpha lipoic acid is an exceptionally versatile nutrient. Being both water and fat soluble, it is able to function in almost any part of the body. It is a potent antioxidant which enhances the activity of vitamins C and E. It is a multifunctional compound providing protection from free radicals and supporting various metabolic processes. It has been associated with supporting nerve health, cardiovascular function, and glucose metabolism.*  

Uses For Alpha Lipoic Acid

Nerve Health:

At this time, as many as fifteen clinical trials have examined the role of alpha lipoic acid in maintaining healthy nerve function. The results of these trials have typically demonstrated that alpha lipoic acid administration provides neuroprotection. In part, this may be due to alpha lipoic acid’s ability to modulate nitric oxide metabolite activity and to promote healthy microcirculation.*

Glucose Metabolism:

Alpha lipoic acid supports healthy glucose uptake and helps to maintain healthy glucose utilization. It also plays a role in moderating the formation of advanced glycation end products.*

Cardiovascular Support:

In addition to supporting healthy glucose metabolism, the antioxidant properties of alpha lipoic acid also promote healthy vascular and blood vessel function.*

Source of Alpha Lipoic Acid

Pure Encapsulations alpha lipoic acid is synthetically produced and has a minimum purity of 99%. Vitamin C (ascorbyl palmitate) is derived from corn dextrose fermentation. Hypo-allergenic plant fiber is derived from pine cellulose.

Potential Side Effects Or Precautions - Alpha Lipoic Acid

If pregnant or lactating, consult your physician before taking this product. Alpha lipoic acid may cause gastrointestinal discomfort in some individuals and should always be taken with meals. In rare cases, alpha lipoic acid may also cause skin rash in sensitive individuals.

Potential Drug Interactions - Alpha Lipoic Acid

At this time, there are no known adverse reactions when taken in conjunction with medications.

Ingredients and Dosage

Alpha Lipoic Acid 400 mg.

each vegetable capsule contains

alpha lipoic acid (thioctic acid) - 400 mg.

vitamin C (as ascorbyl palmitate) - 16 mg.

(hypo-allergenic plant fiber added to complete capsule volume requirement)

Recommended Dosage:

1–2 capsules per day, in divided doses, with meals.

Alpha Lipoic Acid 200 mg.

each vegetable capsule contains

alpha lipoic acid (thioctic acid) - 200 mg.

vitamin C (as ascorbyl palmitate) - 16 mg.

(hypo-allergenic plant fiber added to complete capsule volume requirement)

Recommended Dosage:

1–4 capsules per day, in divided doses, with meals.

Alpha Lipoic Acid 100 mg.

each vegetable capsule contains

alpha lipoic acid (thioctic acid) - 100 mg.

vitamin C (as ascorbyl palmitate) - 8 mg.

(hypo-allergenic plant fiber added to complete capsule volume requirement)

Recommended Dosage:

1–8 capsules per day, in divided doses, with meals.

Alpha Lipoic Acid 600 mg.

each vegetable capsule contains

alpha lipoic acid (thioctic acid) - 600 mg.

vitamin C (as ascorbyl palmitate) - 30 mg.

(hypo-allergenic plant fiber added to complete capsule volume requirement)

Recommended Dosage:

1–2 capsules per day, in divided doses, with meals.

References:

1. Jacob S, et al. Enhancement of glucose disposal in patients with type 2 diabetes by alpha-lipoic acid. Arzneimittelforschung 1995 Aug;45(8):872-874.

2. Ziegler D, Schatz H, Conrad F, Gries FA, Ulrich H, Reichel G. Effects of treatment with the antioxidant alpha-lipoic acid on cardiac autonomic neuropathy in NIDDM patients. A 4-month randomized controlled multicenter trial (DEKAN Study). Diabetes Care.1997 Mar; 20(3): 369-73.

3.Midaoui AE et al. Lipoic acid prevents hypertension, hyperglycemia, and the increase in heart mitochondrial superoxide production. Am J Hypertens. 2003 Mar; 16(3): 173-9.

4. Nagamatsu M et al. Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy. Diabetes Care.1995 Aug; 18(8): 1160-7.

5. Haak E et al. Effects of alpha-lipoic acid on microcirculation in patients with peripheral diabetic neuropathy. Exp Clin Endocrinol Diabetes.2000; 108(3): 168-74.

6. Morcos M et al. Effect of alpha-lipoic acid on the progression of endothelial cell damage and albuminuria in patients with diabetes mellitus: an exploratory study. Diabetes Res Clin Pract.2001 Jun; 52(3): 175-83.

7. Healthnotes Clinical Essentials. Copyright 2004. Healthnotes, Inc.

*This is a statement of nutritional support. This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

This information is for educational purposes only. Consult your physician for any health problems.

Source: Product Information Sheet from Pure Encapsulations

Manufacturers continually change product specifications. While we try our best to keep product descriptions up to date, they do not necessarily reflect the latest information available from the manufacturer. We are not responsible for incorrect or outdated product descriptions and/or images.

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