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Alpha-GPC

What Is Alpha-GPC?

l-Alpha-glycerophophatidylcholine (GPC-choline, alpha-GPC) is a water-soluble phospholipid and neurotransmitter precursor naturally occurring in the body. Unlike most membrane phospholipids, alpha-GPC is water-soluble because it lacks the hydrophobic tail groups.

Uses For Alpha-GPC

Memory And Cognitive Health:

Alpha-GPC passes through the blood brain barrier providing a source of choline for acetylcholine and phosphatidylcholine biosynthesis. By supporting cell membrane fluidity and integrity, phosphatidylcholine enhances healthy neurotransmitter function and signal transduction.

Alpha-GPC may support healthy phospholipid turnover in the brain, helping to counteract age-related cellular breakdown of membrane phospholipids. Acetylcholine is a key neurotransmitter in the brain supporting memory and learning. Optimal phospholipid and acetylcholine levels support cognitive, mental and cerebrovascular health.*

Growth Hormone Support:

Alpha-GPC has the ability to potentiate growth hormone releasing hormone (GHRH), thereby supporting healthy growth hormone (GH) levels. The mechanism of support appears to involve increased cholinergic tone.*

Source of Alpha-GPC

Alpha-GPC is derived from highly purified soy lecithin. Vitamin C (ascorbyl palmitate) is derived from corn dextrose fermentation. Hypo-allergenic plant fiber is derived from pine cellulose. There is no detectable GMO material in this product.

Potential Side Effects Or Precautions - Alpha-GPC

If pregnant or lactating, consult your physician before taking this product. May cause some gastrointestinal irritation, headache or insomnia in a small percentage of people.

Potential Drug Interactions - Alpha-GPC

At this time, there are no known adverse reactions when taken in conjunction with medications.

Ingredients and Dosage:

each vegetable capsule of Alpha-GPC contains

stabilized alpha-GPC (L-alpha-glycerophosphatidylcholine) - 400 mg.
(providing 50% L-alpha-glycerophosphatidylcholine) - 200 mg.

vitamin C (as ascorbyl palmitate) - 20 mg.

(hypo-allergenic plant fiber added to complete capsule volume requirement)

other ingredients: calcium phosphate, silicon dioxide

Recommended Dosage:

3 capsules per day, in divided doses, with or between meals.

References:

1. P M Kidd. Phospholipids: Versatile Nutraceutical Ingredients For Functional Foods. Functional Foods and Nutraceuticals. December 2002.

2. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, Meli M, Panzarasa R. alpha-Glycerophosphocholine in the mental recovery of cerebral ischemic attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci 1994 Jun 30;717:253-69.

3.Parnetti L, Abate G, Bartorelli L, Cucinotta D, Cuzzupoli M, Maggioni M, Villardita C, Senin U. Multicentre study of l-alpha-glyceryl-phosphorylcholine vs ST200 among patients with probable senile dementia of Alzheimer's type. Drugs Aging 1993 Mar-Apr;3(2):159-64.

4.Ceda GP, Ceresini G, Denti L, Marzani G, Piovani E, Banchini A, Tarditi E, Valenti G. alpha-Glycerylphosphorylcholine administration increases the GH responses to GHRH of young and elderly subjects. Horm Metab Res 1992 Mar;24(3):119-21

5. Healthnotes Clinical Essentials. Copyright 2004. Healthnotes, Inc.

*This is a statement of nutritional support. This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

This information is for educational purposes only. Consult your physician for any health problems.

Source: Product Information Sheet from Pure Encapsulations

Manufacturers continually change product specifications. While we try our best to keep product descriptions up to date, they do not necessarily reflect the latest information available from the manufacturer. We are not responsible for incorrect or outdated product descriptions and/or images.

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